Can You Put Neosporin On Dogs Hot Spots? What Are The Risks?

Hot spots, also known as acute moist dermatitis, are localized areas of irritated, inflamed, and often infected dog skin.

Pet owners often wonder if using Neosporin can provide relief and aid in the healing process.

Understanding the potential advantages, drawbacks, and necessary precautions when using Neosporin on dogs’ hot spots can help pet owners make informed decisions about their furry companions’ well-being.

Can you put Neosporin on dogs hot spots? Let’s figure out the answer.

What Is Neosporin?

can you put neosporin on dogs hot spots

Neosporin is a well-known brand of topical medications designed to treat minor wounds like cuts or scrapes.

It consists of a line of antibiotic cream for dog hot spots that help prevent infection in superficial injuries.

The primary purpose of Neosporin is to provide a protective barrier over the wounded area and promote the healing process.

Its formulations typically contain a combination of antibiotics, such as Bacitracin, Neomycin, and polymyxin B, which work together to fight against bacteria.

Moreover, some Neosporin products may include an anesthetic ingredient to alleviate pain and itching.

These products are widely available over-the-counter for human use. So is Neosporin safe for dogs?

Can You Put Neosporin On Dogs Hot Spots? 

Yes. You can put Neosporin on dogs’ hot spots. Neosporin can help prevent infection and promote healing.

However, dogs may lick off the medication, which can be harmful if ingested.

Is Neosporin Useful For Dogs’ Hot Spots? 


Bacitracin can minimize infections after surgery in dogs. One study looked at dogs that had bone surgery.

The dogs were split into groups: some were treated with Bacitracin after surgery, some received no treatment, and some had saline irrigation.

The study found that the dogs treated with Bacitracin had much lower infection rates and fewer positive bacterial cultures than the other groups.

Another study looked at the effects of giving dogs Bacitracin by mouth.

The findings showed that giving dogs Bacitracin by mouth significantly reduced the number of certain bacteria in their intestines.

No major side effects were reported, even when dogs were given too much Bacitracin.

This suggests that giving dogs Bacitracin by mouth can help control the growth of bacteria in their intestines without harming them.


The studies conducted on Neomycin and dogs have been more complex. Neomycin works by suppressing the growth of bacteria, leading to their death within a short timeframe.

It is commonly used to treat infections in the digestive tract due to its poor absorption by the intestines. Neomycin has demonstrated powerful antibacterial properties.

What Are Some Dangerous Problems Of Neosporin Used For Dogs?

Side Effects Of Neomycin And Polymyxin B 

Can I put human Neosporin on my dog? Yes. However, Neomycin in Neosporin can be accompanied by serious side effects when used inappropriately or at incorrect dosages.

One study revealed that intravenous administration of Neomycin in canines resulted in hearing changes, ranging from temporary muffling to complete deafness.

Although these changes were not permanent, they highlight the potential risks of neomycin use in dogs.

On the other hand, Polymyxin B has relatively few negative side effects.

However, one notable adverse effect is the development of Pemphigus Vulgaris, an autoimmune disease that causes painful blistering on the dog’s skin and mucous membranes.

Ingesting Problem 

Can you give a dog Neosporin? You’d better let the pooch take in the Neosporin directly.

When Neosporin is applied topically on dogs, there is a risk that they will lick the treated area and ingest the medication. Ingesting Neosporin can be problematic for dogs.

While the amount of active ingredients in Neosporin is low, regular ingestion can upset the natural balance of microorganisms in the dog’s gut, known as the microbiome.

This disturbance can trigger gastrointestinal issues such as diarrhea, vomiting, and other digestive problems.


Some dogs have a habit of licking everything, including their wounds. While it may seem comforting, the dog licking Neosporin can harm the healing process.

When dogs lick their wounds treated with Neosporin, it can irritate and introduce bacteria into the wound, leading to delayed healing and an increased risk of infection.

How To Use Neosporin As Safe As Possible?

dog hot spot neosporin

Clean And Flush The Wound

Before applying Neosporin, it’s crucial to clean and flush the wound properly. Start by gently washing the wound with mild soap and warm water to remove dirt or debris.

Use a clean cloth or gauze to cleanse the area carefully. Afterward, rinse the wound thoroughly to ensure it is soap residue-free.

Finally, pat the wound dry with a clean, soft towel or sterile gauze.

Do A Small Patch Test

Perform a small patch test before applying Neosporin to ensure your dog doesn’t have an adverse reaction.

Choose a small skin area near the wound and apply a tiny amount of Neosporin.

Observe the area for any signs of redness, swelling, or irritation. Like the Parvovirus shot, Neosporin may ignite allergic reactions.

Stop using it immediately and consult your veterinarian for alternative options if you notice any adverse reactions.

Use Sterile Dressing To Cover The Hot Spots Area

After applying Neosporin, consider using a sterile dressing or non-stick bandage to cover the hot spots area.

This can help protect the wound from further contamination and prevent your dog from licking off the medication.

Ensure the dressing is breathable and secure it gently but not too tight. Regularly check and change the dressing as advised by your veterinarian.

Wipe Off Neosporin After 10 Minutes

Dogs tend to lick topical treatments, including Neosporin.

After approximately 10 minutes of application, gently wipe off any excess Neosporin from the wound using a clean cloth to minimize ingestion.

This helps reduce the amount of medication your dog may ingest. Meanwhile, it still allows sufficient time for Neosporin to provide its antibacterial benefits.

Consulting Your Vet

Consult your veterinarian before using Neosporin or any other medication on your dog.

They will provide specific instructions based on your dog’s condition, the severity of the hot spots, and any underlying health considerations.

They may also recommend alternative treatments or prescribe specific veterinary-formulated ointments or creams.

What Are Other Better Alternatives To Neosporin For Dogs? 

Banixx Sprayer

Banixx is an antimicrobial spray specifically formulated for pets. It contains stabilized hydronium 2.5% as its active ingredient.

This unique pH formulation creates an acidic environment that helps lower bacterial toxicity and increase antimicrobial activity.

The spray’s elevated oxygen levels further enhance its antibacterial properties.

Banixx can support advanced wound healing, control infections, and promote healthy tissue regeneration.

It is safe for dogs and can be sprayed directly onto the affected area for wound care.

Antimicrobial Wound Cream

This is a non-toxic wound cream designed for animals. It provides antimicrobial properties to ward off infection and promote healing.

The cream can be applied topically to a minor cut or scrape, and dog abrasions.

It is safe even when your pets lick it. Vetericyn Plus is known for its gentle and effective wound care properties.

Thus, it can keep the wound clean and create an optimal environment for healing.

Douxo S3 Pyo Shampoo

Douxo S3 PYO shampoo is a shampoo made for pets with itchy skin. It contains chlorhexidine, which has antiseptic, antibacterial, and antifungal properties.

This shampoo can clean your dog’s wound and help remove debris and bacteria, reducing the risk of infection.

The gentle formula is good for dogs with sensitive skin and can be used as directed by your vet for wound care.

Dog-Safe Wipes

Like Douxo S3 Pyo shampoo, dog-safe wipes such as Mal-a-Ket are safe for dogs. It has chlorhexidine, which is known for its antiseptic properties.

These wipes can gently clean your dog’s wound and treat hot spots. They remove dirt, bacteria, and debris from the wound, leaving a clean environment for healing.

The wipes are easy to use and can be used for spot cleaning or larger wound areas. Just follow the instructions on the packaging for proper use.

Manuka Honey

Manuka honey is a special type of honey from the nectar of the Manuka tree in New Zealand.

It is known for its antibacterial properties, mainly because it has a high concentration of methylglyoxal.

You can put Manuka on minor wounds or hot spots on dogs. It creates a protective barrier on the wound to prevent infection and assist in healing.

However, it’s important to use Manuka honey sparingly and ensure your dog doesn’t eat too much.

What Should You Do In The First Two Hours After You Notice A Hot Spot?

antibiotic cream for dog hot spots

Check The Spot

Take a closer look at the hot spot and gather important information about its appearance. Note the color, size, swelling, and any signs of bleeding.

It’s helpful to take a photo of the hot spot for future reference or to show your veterinarian if needed.

Choose A Proper Treatment

You can proceed with home treatment if the hot spot appears relatively mild and not infected. Safely trim any hair around the area that might interfere with the medication.

Sterilize the hot spot with an over-the-counter hot spot spray or chlorhexidine, following the instructions provided.

Leave the product on hot for 10 minutes, then rinse with clean water.

Another option is using a hose to apply the pressured spray to remove bacteria and debris but stop if it causes discomfort to your dog.

Once the area is dry, apply a thin layer of topical hot spot ointment or spray. Regular Neosporin can be used, but wipe off any excess after 10 minutes to prevent ingestion.

Call A Vet If Necessary 

If the hot spot appears infected with pus, significant bleeding or shows signs of severe redness and tenderness, it’s important to contact your veterinarian for an appointment.

An infected hot spot may require prescription medication for proper treatment.

If it’s your dog’s first hot spot or if your dog frequently experiences hot spots without a clear cause, it’s best to consult with a veterinarian.


When Should You Use Neosporin?

Neosporin can be used on dogs for small cuts or scrapes that aren’t too severe or deep.

If your dog has a minor skin injury that is clean and free of debris, you can apply a thin layer of Neosporin to help prevent infection and promote healing.

However, you shouldn’t use Neosporin on large or deep wounds. It’s advised to talk to a vet for the right treatment in these cases.

What Should You Do When Your Dog Licks Neosporin?

Prevent further licking

Licking the Neosporin off the wound can interfere with its effectiveness and may lead to further irritation or infection.

Use an Elizabethan collar (cone) to keep your dog from accessing the treated area.

Alternatively, you can cover the wound with a dog-friendly bandage or dressing to discourage licking.

Clean the wound

If your dog has already licked off the Neosporin, clean the wound gently with mild soap and water. Pat it dry and reapply a fresh Neosporin layer if your veterinarian recommends it.

How To Prevent Hot Spots On Dogs?

To keep hot spots at bay on dogs, you can manage external parasites and check ears and tail regularly.

Besides, monitoring problem areas, rinsing and drying after swimming, and maintaining a clean environment are good options.


Can you put Neosporin on dogs hot spots? Yes. But it may pose some potential risks if the dogs lick the cream off.

There are also some safer treatments available for your dog than Neosporin. It’s always recommended to consult with a veterinarian for the best course of action for your furry friend.


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Hi I am Mitchell. Dog Growth is a blog about dog caring and training where I share my experiences to my community. Hope you enjoy it!

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